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Botox injections contain some ingredients extracted from Botulinum toxin- a deadly poison which is produced from the clostridium botulinum strains of bacteria. A positive use for this strain of bacteria was not discovered until 2 decades ago and till present moment this powerful potent substance has been approved by the Food Drugs and Administration{FDA} for the treatment of several disorders , including; glabellar rhytides, cervical dystonia, and many others.
Hyper functional lines on the skin especially on the face have been successfully removed through the use of Botox injections. These hyper-functional lines often make people look like they are angry, fearful, or fatigued. Most surgeons use excision methods, and implantation of silicon and other means to remove such lines but it is believe that such methods result in temporary effects. The regions where Botox injections are mostly applied are fore head areas, Glabellar, and periorbital crow’s feet.
The contraction of the underlying facial muscles usually leads to hyper-functional lines. Toxin A is one of the anti-genically distinct extracts used for the treatment of hyper-functional lines on the face. Botulinum Toxin A { or Botox} works by causing a paralysis by inhibiting the release of acetylcholine at the neuro-muscular junction of the face. This partial paralysis is accomplished in the steps.
The first step involves the binding of the nerves in the skin region by toxins, the second step involves the internalization of the toxins into the nerves of the skin tissues, and lastly , the internal proteolytic enzymes cleave the toxins for the final stage of treatment. At the third stage, the degradation by products included in the Botox injection will interfere with the vesicle fusion of the plasma membrane. The final procedure results in the inhibition of the acetylcholine activities.
The Botox injections for improving facial aesthetics is expected to take between 24 to 72 hours to achieve a full effect, some individuals may require more than 3-4 days to achieve a significant effect but such cases are quite rare. The dose of the BOTOX toxin is normally measured in 1 standard unit, and the effect of the injection may last between 8 to 12 weeks.
The Botox injection therapy is not for everyone, individuals who are pregnant or lactating mothers are not expected to use this injection because it may counter-react in several ways. Individuals who have an history of reactions to toxins may also be persuaded not to take the injections. Individuals younger than 12 and those who suffer some infections at the injection sites are also encouraged to discontinue such procedures.
Individuals who are suffering from some existing neurone diseases are also disallowed from using Botox injections. In the administration of Botox injections on a patient several pre-inspection procedures are conducted especially on the skin of the patient, attention is normally focused on individual patients who have tendencies to counter-react with Botox injection and the physician try to see if such patients can cope. A patient that feels he has not achieved significantly with the first Botox injection may check-in for another injection which could take place at least 1 week after the first injection.
Once a patient is satisfy with a Botox injection, the next appointment should be around 2-3 months after he first visit.
The most feared possible side effect of Botox injection is partial paralysis of the face { especially the treated area}, Bruising problems may also occur at the region that has been lacerated on the face, while minor complications such as sleep apnea , slight headaches and the likes may also occur . Most side effects that occur from Botox injections will last for few minutes or days.
